Reproductive Immunology can prevent miscarriages Reproductive Immunology Associates Reproductive Immunology can prevent miscarriages
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Reproductive Immunology Laboratory Panels: When to Test


Recurrent Miscarriage
Test 12 weeks
pre-procedure
Upon confirmation
pregnancy (+HCG)
Every 4 weeks
through 24
12 & 24 weeks
gestation
APLA X X X  
APA X X   X
ANA X X   X
IP X X   X
NKA X X   *
DQA X      
DQB# +      
F II P X      
F V L X      
MTHFR X      

Infertility, pre-IVF/ET
Test 4 weeks
before procedure
4 weeks
gestation
12 weeks
gestation
 
APA X X X  
ATA X      
IP X X X  
NKA X X *  
DQA X      
DQB# +      

# Investigational
* Repeat if IP is abnormal
+ Perform on male if couple shares DQA 4 or if male is DQA 2, 2

ANA - Antinuclear Antibodies
APA - Antiphospholipid Antibodies
APLA - Antipaternal Leukocyte Antibodies
ATA - Antithyroid Antibodies
DQA - DQ Alpha
DQB - DQ Beta
IP - Immunophenotype
NKA - Natural Killer Cell Assay
F II P - Factor II (prothrombin) Mutation
F V L - Factor V Leiden Mutation
MTHFR - Methylene Tetrahydrofolate Reductase Mutation